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ICIC
The
International Conference in Trends for Scientific Information
Professionals
Sitges (Barcelona) Spain. 21-24
October 2007
This page last updated 10 October 2007.
Programme as of this date
This year the ICIC meeting will cover
trends in the field of scientific and professional information.
The 2007 meeting programme has an impressive line-up of significant
figures in the information world. Among the topics covered and
discussed by the 20+ speakers are:
- tools for intelligence and decision
support, including mining chemical and biological data, visualisation,
information and entity extraction followed by a panel
discussion.
- the new patent landscape, text and
structure searching, free patent services, search and substructure
searching followed by a panel discussion.
- search engines and data integration.
- new business and information centre
models ...
The meeting features a pre-conference seminar
given by Prous Science (link below), as well as a post-conference tutorial
given by Stephen Arnold (link below).
PROGRAMME
Sunday 21 October 2007
17:00 Prous Science Seminar: with keynote speaker
Jeffrey S. Ross (free registration
required)
19.30 Welcome Cocktail and Dinner
sponsored by Prous Science
Monday 22 October 2007
® Opening Keynote
08.30
David E Martin
M-CAM, USA
Innovation and the Birth of the Fusion Economy: Financial
Implications of Intellectual Property
At the dawn of the 21st century, we face the
realisation that the tangible economy and its attendant modes
can no longer be represented or financed using the convention
of the balance sheet. Presaged with the collapse
of the 2001 WTO debates in Doha, heralded with the recent stock
market multiple personality disorder, and against the growing
drumbeat of currency strain, global finance is about to experience
the collapse of the tangible, industrial market paradigms and
the emergence of the intangible, asymmetric risk capital era.
- In 2005, the US and international governments
cancelled or curtailed sovereign immunity from infringement liability
previously afforded to government contractors. In 2006, the US
Justice Department argued to encourage patent infringement when
it feared the loss of Blackberry, while the Commerce Department
decried intellectual property abuses in China.
- In 2008, all banks and financial institutions
will have to test their loss reserves for their exposure to intangible
economy risks under the Basel II Accords. Neither their
internal systems nor external business practices are prepared
-- anywhere.
- Over $1.5 trillion in uninvested capital
in the Islamic world -- estimated to grow to as much as $3 trillion
by years end -- directly or indirectly stands ready to
move into diversified currencies further destabilising weakened
dollars, yens and euros.
- Infrastructures designed to arbitrate to
whom proprietary limited monopolies are granted have been shown
to be unsustainable and overly provincial giving rise to the
emergence of sovereign-backed monopolies.
- The presumed hegemony of the Trilateral countries
in terms of invention and innovation is increasingly challenged
by the Silk Road Axis.
A discussion of these events (and their consequences)
will be presented together with a series of anticipatory scenarios
to explore the strategies to adapt in this financial transformation.
Day One Conference Opening
Session 09:10
Martha Ellison
3M Information Research & Solutions, Minnesota, USA
Mapping and Driving the Knowledge Solutions of a Corporate
Information Organisation Towards 2010
Throughout 2004 and early 2005, the management
team of 3Ms worldwide information organisation undertook
a project to envision the staff, services and resources needed
to support 3Ms information requirements in 2010. Using
several intersecting strategic planning processes, a map for
the future was created along with a plan for closing the gaps
to meet future organisational needs.
This presentation discusses the strategic planning processes
used, the outcomes, and recent adjustments required to maintain
alignment between the information group and 3Ms changing
corporate strategies. New models necessary to stay on the path
to 2010 are described including mass customisation, prioritised
intermediated information research, and libraries as innovation
spaces.
Michael Kayat and Alan
Porter*
UTEK Corp, Florida, USA and *Georgia Tech, USA
White Space Analysis for Biomaterials in Complex Patent Landscapes
The development of biomaterials is accelerating
in many areas of medical and surgical devices. There are an increasing
number of biomedical application areas, from cardiovascular and
dental, to ophthalmologic, orthopaedic and urological treatments.
There is also an increasingly complex patent landscape emerging
that covers fundamental areas such as surface modification and
characterisation of biomaterials which are important for drug
delivery systems, tissue engineering and implants. The paper
describes an approach using advanced text mining with concept
maps, together with large scale patent analysis that provides
a path for discovering new patent white spaces. We also discuss
a methodology for mapping new potential innovations.
Product Highlights: Prous /
Thomson Scientific / CAS-STN
10:35-11:05.
Break, Networking and Exhibition
Michael Hehenberger
IBM Healthcare & Life Sciences, New York, USA
Text Analytics and Chemical Annotation of Patents and Biomedical
Literature
Bio-pharmaceutical industry is challenged
to replace drugs that come off patent with novel approved medical
treatments that meet increasing FDA safety and efficacy demands.
Therefore, the status of Competitive Intelligence has risen from
a support function to a strategically important discipline at
the core of investment decisions, mergers, acquisitions and licensing
activities. In addition, there is an increasing need to identify
new drug candidates and other Intellectual Property for licensing.
We propose a solution that complements the search and mining
of IP / Patents and biomedical literature with an innovative
approach toward the annotation of domain specific entities, including
chemical names. Those chemical names of arbitrary complexity
are linked to chemical structures, represented by Smiles strings.
Our approach will render the scientific literature and patents
searchable by web-enabled chemical structure/substructure search
applications.
Our solution includes a data warehouse that can contain both
structured and unstructured data, along with chosen annotations.
IBMs Blue Gene supercomputer is used to increase search
and annotation performance. By means of Blue Gene we are able
to populate and query the data warehouse rapidly, and optionally
to add computed properties to given chemical entities. The presentation
will include a brief demonstration of the solution.
Product Highlights: Questel
/ Elsevier / TEMIS
Nicko Goncharoff
Reel Two, USA / New Zealand
Combining Text and Structural Search in the Chemical Literature
A fully effective search tool
for chemists requires access to both unstructured textual sources
as well as structured chemical information. This presentation
looks at two of the challenges this presents. First, how to extract
information from unstructured text such as patents or the academic
literature. Second, how to conduct searches across disparate
sources of information -- that is, how both document similarity
and chemical similarity can be combined in a single similarity
search. Such a search might start with a portfolio of patents
together with some keywords and chemical structures. The search
would find those patents which both use similar language in the
text and which reference the chemical structures. The search
can then be refined iteratively by including or excluding any
of the items returned by the search: documents, words, phrases,
structures or fragments; and then repeating the similarity search.
Consideration will also be given to the challenging environment
for such searches where there are very large numbers of documents
(tens of millions of patents) containing many structures (millions
of chemical structures).
Robert Stewart
Thomson Scientific, Pennsylvania, USA
Uncovering Competitive Technology Intelligence from Chemical
Information in Patent Databases
There is a large amount of
chemical information contained in commercially available patent
databases. Uncovering that information is relatively straightforward,
but converting it into intelligence is often more challenging.
This presentation examines several methods for turning chemical
information from patents into actionable intelligence. At one
end of the spectrum are tools that are readily available to most
information professionals, such as Microsoft Excel and simple
analysis tools that are built into commercial search engines.
At the other end are sophisticated text and data mining tools
that can uncover hidden intelligence from lists, matrices and
relationship maps. The presentation shows that it is often possible
to uncover intelligence with the simpler tools, while discussing
situations where the more sophisticated tools add value.
Product Highlights:
European Patent Office / Minesoft
13:00-14:30
Lunch, Networking and Exhibition
® After Lunch Keynote 14:30
Nick Baker
Reed-Elsevier UK
A Perspective on the Evolution of Information Business Models
This introductory keynote
will look at the range of business models extant in professional
and business information markets, trends in business models change
and implications of these changes. The review will cover subscription/licence,
advertising/sponsorship and the emerging feasibility of more
"open" and network/community models. A range of examples
will be covered across a number of information markets.
James Ryley
FreePatentsOnline.com, USA
Using Conceptual Search in Scientific, Financial and Intellectual
Property Databases
Traditional search engines
require that matching documents contain nearly the
exact words or phrases used in the query. Such search engines
cannot identify relevant documents which use synonymous, but
not identical, terminology. As a result, finding important documents
can be difficult due to the need to guess what terms an author
would have used when describing a given concept. Conceptual Search
addresses this problem. Sophisticated statistical techniques
are used to group documents into topical categories, and to build
a database of synonymous terms. Then, when a search is performed,
all synonymous terms that are related to the searchers
input are considered not just the literal terms in the
query. At the same time, the topical groupings permit the conceptual
search engine to ignore documents that contain the literal words
in the query, but which are nonetheless irrelevant to the searchers
needs. The result is a search engine which has a high retrieval
rate (recall) and excellent ability to discriminate relevant
from irrelevant documents (precision). Using such a search engine,
searchers can search faster, and have greater confidence that
all relevant documents have been located.
Product Highlights:
Springer / Domex e-Data / Lexis-Nexis
Jane List
The Technology Partnership, UK
From Esp@cenet to Google: The New World of Free Patent Searching
Google caused great debate
amongst the patent searching community at the beginning of 2006
by unveiling a beta-test search engine for US patents. But how
good are free patent databases on the internet? The new patent
databases are certainly opening up the world of patent searching
to more people; inventors, laboratory scientists and engineers
are carrying out patent searches. But is there a place for them
in the professional patent searchers tool-kit?
This presentation starts by looking at databases from the patenting
authorities such as EPO, JPO and USPTO and then beyond to the
more recent developments in free patent search engines from free
patents online, fresh patents and Google. These sources are compared
for functionality, usability and also coverage and timeliness;
all important criteria for a comprehensive patent search whether
for freedom to operate, prior art, research or validity purposes.
The presentation is illustrated with examples from ultrasonic
devices, micropumps and other typical searches from The Technology
Partnership which support our developments of next generation
physics-based products.
16:25-16:55
Break, Networking and Exhibition
Nigel Clarke, V. Hassler, M. Szubert
European Patent Office, Austria
Possibilities for Chemical Structure Searching in esp@cenet
The EPO's free web-based esp@cenet
service provides an entry level to patent information novices
or to more experienced searchers when beginning a new search
before moving on to more sophisticated searches. Search term
input is via search masks, and allowed search inputs may be conveniently
grouped into "parameters": eg, publication date, publication
number etc, "classification symbols": IPC or ECLA codes,
"proper names": inventor name, applicant name, or "keyword".
The keyword input in esp@cenet can be used to search in the title
field or the title and abstract field. Many technical fields
such as mechanical engineering are tractable by keyword searching,
However a recent profiling survey of esp@cenet users showed that
two of the largest user groups are from the chemical and pharmaceutical
sectors. Much chemical patent and journal literature searching
in commercial and public domain databases is carried out using
chemical structures, ie, the allowed search input is a chemical
structure, written, drawn or selected from a library, by the
searcher. This input is then used by search engines to interrogate
databases, and retrieve the relevant documents, patents or journal
articles for example. Keyword searching on its own is not the
most effective way to search chemical or pharmaceutical literature.
The current esp@cenet search engine does not support chemical
structures as input, however it does support keyword searching.
In view of the utility of chemical structure searching to chemists
or pharmacists, but with the restriction of searching to keywords
(chemical names) in esp@cenet, it was decided to investigate
the possibility of deriving chemical names from structures identified
by the user, and using those derived chemical names as search
input for esp@cenet. This paper reviews the R&D work which
has identified the necessary building blocks to facilitate the
process for structure searching in esp@cenet; Draw/select structure
=> convert structure to unambiguous code => convert unambiguous
code to chemical name => identify synonyms => present user
with synonyms => search with synonyms in esp@cenet.
An overview of the possible public domain software which could
be used to build such a process will be presented, and from this
the way to a possible chemical structure "translation engine"
adapted for esp@cenet will be indicated. The anatomy of an idealised
chemical structure search incorporating classifications will
be demonstrated. Some of the remaining difficulties which present
obstacles to progress will be discussed.
®
The Patent Panel 17:20
An interactive panel, animated
by Jacques Michel
that unites an expert panel with the audience for comments and
questions in the patent and free services area. Expert panellists
include Minoo Philipp (Henkel), Peter
Vanderheyden (LexisNexis), Willem-Geert Lagemaat
(Patcom) and James Ryley (FreePatentsOnline)
18:45 ICIC Conference Cocktail
Sponsored by Questel
Tuesday 23 October 2007
® Session
Starts 08:00
Rudy Potenzone
Microsoft, Washington, USA
A Knowledge and Content Management Strategy for the Pharmaceutical
Knowledge Worker
James Rizzi
Array Biopharma, Colorado, USA
Development and Deployment of an Information-Centric Tool
for Better Decision Making in Drug Discovery
The drug discovery process and the pharmaceutical
industry in general are beginning to face a real challenge: How
can we maintain scientifically sound decision making and effective
project management as the volume of data burgeons? Today there
are few good enterprise solutions to this problem and usually
organisations resort to email, Excel, and PowerPoint. In order
to address this issue more effectively, better data management
tools are needed.
Array is collaborating with General Dynamics VIZ to apply those
advances to drug discovery and development command and control.
The solution relies on their core technology platform to create
an information-centric tool referred to as CoMotion Discovery.
With this tool, a projects plan, work progress, scientific
results and management decisions across multiple data sources
are integrated, updated and disseminated automatically through
a single interface. Team members can collaboratively review data
and annotate the results with their thoughts and intuitions (soft
information), and link out to more details, supporting data or
other related information. This presentation focuses on both
the technical and cultural issues encountered with the development
and deployment of the CoMotion Discovery tool.
Product Highlights: Bizint
/ Reuters / Vivisimo
Gilles Montier
TEMIS, France
Applying Text Analytics to the Patent Literature to Gain Competitive
Insight
Intellectual property management
is a critical business process for organisations willing to protect
existing products, foster innovation and increase revenue. But
prior art analysis has become increasingly difficult in all industries,
due to the number and the complexity of documents to analyse.
Additionally, monitoring the competition R&D efforts is becoming
more difficult and more resistant to manual analysis. This trend
has been especially accentuated in the life sciences, with the
ever increasing competition from generic and me-too
drugs and the importance of licensing in and out drugs and molecules
within the portfolio of all major players.
Patent specialists need to sift through large collections of
patent documents, looking for specific clues. Online databases
and visualisation tools provide a first answer to those questions
but fail to offer a user-friendly environment to analyse the
content of patents in a flexible and precise way. This presentation
illustrates some real-life examples of in-depth patent analyses
leveraging Text Analytics technology for relevant entities extraction
(genes, diseases, chemical compounds, molecular targets).
Achim Zielesny and S. Neumann*
University of Applied Sciences of Gelsenkirchen, Germany, and
*GNWI, Germany
Intelligent IT-Systems? Challenges, Fakes and
Hard Science
The basic feature of an IT system that pretends
to be intelligent is its capability of a specific
kind of human-like understanding of the tasks for which it is
designed. The challenges of a human-like understanding are described
in general as well as their consequences for current scientific
retrieval systems. In conclusion, the majority of todays
intelligent systems are classified as fakes
which does not necessarily restrict their practical usefulness.
This is outlined with an example from intelligent text-mining
in Bioinformatics. Finally, intelligent hard-science methods
are discussed and demonstrated that circumvent basic problems
of fakes but have limitations of their own.
Product Highlights: EBSCO /
Search Technology
10:40-11:10
Break, Networking and Exhibition
Stephen Arnold
AIT, Kentucky, USA
Text Mining and Discovery Functions in the Chemical and Pharma
Domains
Text mining and content discovery
functions are becoming a basic function of enterprise applications.
Smaller firms can match the intelligence and analytic functions
of the largest organisations at greatly reduced costs. The reason
for this development is that text mining functions have been
embedded into enterprise applications, from Oracle's database
to Microsoft's servers. One licence fee brings multiple tools.
This shift is in response to demand for systems that can help
manage the large flows of information in chemical or pharma companies.
A related development is that enterprise search system vendors
have aggressively adopted text mining as a quick fix to their
precision and recall woes. Fierce competition ensures that the
licence fees for such systems will continue to drift downward
and lead to easier integration among enterprise applications.
Commoditisation of advanced text processing creates a number
of opportunities for vendors to fill needs for specialised functions.
Debra Banville
AstraZeneca, Delaware, USA
Mining Chemical and Biological Information from the Literature:
Finding the 'Right Stuff'
It is easier to find too many
documents on a particular life science topic, than to find the
right information inside these documents. With the application
of text data mining to biological information, and the explosion
of HTS data, it is no surprise that researchers are starting
to look at applications to extract chemical information. The
mining of chemical entities, both names and structures, brings
with it some unique challenges. Ultimately, text data mining
applications need to focus on the marriage of biological and
chemical information.
Commercial and academic efforts are beginning to address these
challenges. Developments in the World Wide Web are changing the
way researchers and publishers look at published information
and the way researchers from industrial and academic institutions
interact with each other and with that information. This presentation
explores ways in which all these changes can coalesce into something
tangible for a researcher to navigate, and how researchers can
infuse their knowledge and experience into the process of literature
research. Finally, we consider how this information can be managed
over time to find the 'right stuff'
Product Highlights:
Scipat / QWAM / Intellixir
12:35-14:15
Lunch, Networking and Exhibition
Josep Prous
Prous Science, Barcelona, Spain
Knowledge-Based Drug R&D Productivity Maximisation
The extensive use of virtual screening techniques
and combinatorial chemistry in recent years have brought investigators
and researchers large sets of compounds to be tested. The latest
trends are focused on the intelligent selection of these compounds
for specific targets.
BioEpisteme, a knowledge-based project, was initiated to contribute
to the faster discovery of new and safer drugs, as well as the
finding of new uses for known molecules. In-house developed datamining
algorithms have led to a model that characterises more than 400
different molecular mechanisms of action simultaneously. Millions
of molecules are being used to develop the project.
Additionally, the safety of drugs used in clinical practice is
under constant scrutiny and the withdrawal of several compounds
in recent years confirms the productivity challenges faced by
modern biomedical research. In this context, the BioEpisteme
technology has been used with success to build models that discriminate
between active and inactive compounds for specific pharmacological
activities, and to differentiate drug from non-drug compounds.
The development of the BioEpisteme Project and its application
in high-throughput virtual screening, drug repositioning and
ADMET assessment will be presented.
Marc Zimmermann, Juliane Fluck, Christoph
M. Friedrich and Martin Hofmann-Apitius
Fraunhofer Institute for Algorithms and Scientific Computing,
Germany
A Critical Review of Information Extraction Technologies in
Chemistry
Retrieval of relevant information in the area
of chemistry remains a challenge. Recent progress in the area
of information extraction technologies promises to solve a broad
spectrum of problems associated with the time consuming tasks
of finding all relevant information, finding
all relevant mentions and relationships and making
all this information available to an entire community / organisation.
However, despite the attractive perspectives of fully automated
information extraction, there is considerable discrepancy between
the promises of vendors of information extraction technology
and the true problem solving of real existing problems in the
day-to-day work of researchers and patent specialists.
This presentation reviews some of the recent benchmarking activities
in the area of information extraction, with a special focus on
named entity recognition and relationship mining. It sheds some
light on recent research in the area of information extraction
from chemical structure depictions, as communication of chemical
information through images is one of the preferred routes taken
in chemistry and pharmaceutical sciences. The presentation combines
an overview on technological approaches with a critical review
of performance measures and the outcome of critical assessments
and benchmarking activities in the scientific community.
Product Highlights: Treparel
/ InfoChem / Digital Chemistry
15:40-16:10
Break, Networking and Exhibition
Steve Papa
Endeca, Massachusetts, USA
Where Do Search and Business Intelligence Meet Today?
The Search and Business Intelligence markets
made some surprisingly swift, significant movements towards each
other in the past year. At industry analyst IDC, the Content
team led by Sue Feldman and the BI team led by Henry Morris released
a series of research reports on the fast emergence of "unified
access" applications that are blurring the boundaries between
these two fields of information access. Within months, BI giants
Business Objects, Cognos, and Oracle all announced major new
search features and products.
This convergence opens a rich area of study. At the outset, it
touches the antipodes of unstructured versus structured content,
atomic views versus aggregate views, and casual users versus
trained users. For early adopters of unified access applications,
it is already introducing functionality previously unavailable
in either market. This presentation shows examples from high
seat-count deployments where enterprise users are finding the
information they need in unprecedented ways when Search and Business
Intelligence converge.
®
The Mining Panel 16:40
An interactive panel, animated by
Martin White (Intranet Focus) that unites an expert panel with
the audience for comments and questions in the text and data
mining areas. Expert panellists include Charles Huot (TEMIS),
Wolfgang Thielemann (Bayer Healthcare) and Stephen Arnold (Arnold
IT).
®
Web2.0@Work 17:40
Currently there is considerable interest
and debate around the use of Web2.0 tools, ie, wikis, blogs,
etc, and how they can be used to support collaboration and knowledge
sharing within the business environment. While a lot has been
written about these tools and how they could be used, there are
not many actual use case examples around. The aim of this session
is to allow interested participants to discuss real use case
examples and share their successes and failures when trying to
implement.
This session, led and animated by Ben Gardner of Pfizer, will
be run in an informal unconference style where open participation
from those present will be actively encouraged. Short 5-10 minute
ad hoc presentation from the floor will be welcome. This is designed
to be an informal session among friends, so please feel relaxed
and free to present however you want -- experiment with a different
style, use PowerPoint, talk to a screen (demo), simply engage
us in some discussion; the choice is yours! Join
the pre-conference working group.
19:30 Conference Reception
and Dinner
Sponsored by CAS and Thomson Scientific
Wednesday 24 October 2007
® Session
Starts 08:30
Product Highlights:
InfoApps / IntraFind / Linguamatics
Simon Gittins
Vivísimo, USA
Collaboration, Folksonomy, Web 2.0 Buzz Terms or Reality?
To move beyond the buzz of
Web 2.0, enterprises need to remain focused on the tasks and
business goals at hand. All new features must be easy to use
and align with the current work flow of end users, or else they
will simply not use the new tools provided. Enterprise search
is the connector into all enterprise applications, so it makes
the most sense to serve as the home for all new collaboration,
tagging and sharing functionality. By building upon existing
search applications, enterprises are increasing the value and
use of information ultimately improving the performance
of individual employees to meet the strategic goals of the corporation.
This presentation describes how Web 2.0 functionality can be
integrated into an enterprise search application and examines
benefits and solutions of using Web 2.0 functionality.
Ben Gardner
Pfizer, UK
Strategies for the Integration of Information
Integration of information
from diverse sources in support of business needs is one of the
key challenges currently faced by information services groups.
Historically, data have been stored in stand-alone databases
designed to support specific information requirements. While
this strategy was optimal for the core user groups, it limits
the re-use of the information and prevents the realisation of
synergies obtainable from combining diverse data sources. If
we are to obtain the maximum value from our data we need to develop
both dynamic and static strategies that support the integration
of data sources. The established approach to data integration
traditionally involves some form of data warehousing and the
building of formal ontologies, taxonomies, indexes, etc. This
presentation illustrates with case examples a number of different
approaches that have been used at Pfizer. In addition, it considers
whether there may be an alternative approach and what we can
learn from Web2.0 culture.
Wolfgang Thielemann
Bayer Healthcare, Germany
Information Extraction from Full-Text Challenges and Opportunities
New technologies like
taxonomy based categorisation or text mining enable information
professionals to analyse efficiently large amounts of text information.
Initially many of these technologies were developed for the analysis
of business news and biological target interaction. Currently
they are expanding to other life science relevant areas such
as chemical or clinical information. Although the available applications
have become powerful, there are still many problems to solve.
This presentation highlights challenges as well as opportunities
and compares the results with those we know from searching indexed
databases.
10:30-11:15
Break, Networking and Exhibition
Daniel Domine, C. Merlot, M. Ibberson
and
M. de Francesco
Merck Serono, Switzerland
Integration of In-House and External Data in Practice
This presentation begins by
looking at the current situation in data integration in Pharmainformatics.
It considers production workflows versus entity aggregation,
the integration and exploitation of external data sources, and
discusses and illustrates structured, unstructured and "thought-to-be"
structured information. In conclusion, the presentation looks
at some examples of successful integration and discusses future
directions.
Wendy Warr
Wendy Warr & Associates, UK
Social Software: Fun and Games, or Business Tools?
This is the era of social
networking, collective intelligence, participation, collaborative
creation, and borderless distribution. Every day we are bombarded
with publicity about collaborative environments, newsfeeds, blogs,
wikis, podcasting, webcasting, folksonomies, social bookmarking,
social citations, collaborative filtering, recommender systems,
media sharing, massive multiplayer online games, virtual worlds,
and mash-ups. This sort of anarchic environment appeals to the
digital natives, but which of these so-called Web 2.0
technologies are going to have a real business impact on the
chemical and pharmaceutical industries? How will the issues of
quality control, spam, security and privacy impact the implementation
of social networking in hide-bound, large organisations? This
presentation will cut through the hype and make some predictions
about information management in 2012.
Barbara Gilmore-Halliwell
and Diane Webb
KAI Pharmaceuticals, and BizInt Solutions,
California, USA
Drug Portfolio Analysis Targeted Anticancer Therapies
The success of the pharmaceutical
industry depends on the efficiency of the drug development process
and the availability of new targets. In addition to small molecule
drugs, the market for monoclonal antibodies is expanding, as
are advances in recombinant and formulation technologies. There
has been a shift in oncology. Cancers are no longer defined solely
from the organ of origin, rather, the genetic changes to the
complex pathways controlling signal transduction and cell cycle
checkpoints. This shift parallels the emergence of targeted
therapies. Targeted therapies inhibit pathways involved
with the initiation or promotion of cancer or to promoted pathways
involved with the apoptosis of cancer cells. Understanding what
is in the various drug pipelines relating to targets is critical
to informed decision making processes within companies.
Multiple drug pipeline databases play a key role in understanding
the competitive landscapes. This paper discusses several case
studies surveying the competitive landscape relative to the stage
of drug development, focusing on the five leading drug pipeline
databases: ADIS R&D Insight, IDDB, IMS R&D Focus, PharmaProjects,
and Prous Integrity. Differences exist in coverage and content.
Draw insights for your own research and access information critical
to your collaborative decision making processes as your companies
develop portfolios of innovative therapies. The paper concludes
by offering explanations for differences in coverage and content,
and shows how to connect the dots from the places where the information
resides to the people who need it.
end of 2007 conference approximately
12:45
View 2007 hotel venue
View Programme Committee and Strategic Advisory
Board members
To record your interest and to be on our email update
list for this and future meetings your
interest
Wednesday 24 October 2007 (post-conference tutorial)
Text Mining: Placebo
or Scopolamine for Patent Analysis,
Pharma Research and Business Intelligence?
Stephen E. Arnold
President
Arnold Information Technology
details of the post-conference
tutorial
|